NCBS is looking for a creative and highly motivated Postdoctoral researcher to join the research group of Dr Sabarinathan Radhakrishnan at NCBS to study the impact of chromatin architecture on somatic mutational processes and gene regulation in cancer, funded by DBT/Wellcome Trust India Alliance.
The broad aims of this project includes (a) How does three-dimensional chromatin architecture impact the basic biological processes such as DNA replication and DNA repair? (b) How does that influence the generation of somatic mutations at specific regions of the genome? And (c) Can those mutations affect the local chromatin architecture and thereby cause any phenotypic effects?
- Ph.D. in Molecular Biology/Biotechnology or related field with experience in cancer biology.
- Experience with mammalian cell culture, stable cell line generation and molecular biology techniques such as Western blotting, Cloning, immunostaining, DNA/RNA extraction and quantification, and high throughput assays to understand DNA-protein interactions and gene expression. Experience with genome editing techniques (e.g., CRISPR/Cas) is a plus.
- A strong interest to develop and implement single-cell genomics approaches and data analysis will be preferred.
- Submission Deadline: 10th March 2021
- Preferred Joining Date: 1st May 2021
Initially one year, which is extendable upon evaluation.
Interested applicants should email to Dr Sabarinathan Radhakrishnan (email: sabari[at]ncbs.res.in) enclosing:
- CV (with the names and contact details of at least two scientific referees)
- Summary of previous research work, statement of research interest and suitability for this position.
Please mention the advertisement number in the subject line. Incomplete applications will not be considered. Shortlisted applicants will be invited for an online interview which may comprise multiple rounds to assess the candidate’s fit for the position.
As per the Department of Biotechnology, Government of India guidelines.